• Understanding and defining these miRNA profiles helps

  2019-05-06

  

  Understanding and defining these miRNA profiles helps to uncover the clinical usefulness of miRNAs. Numerous human clinical trials are currently evaluating miRNA therapeutics during various liver diseases, such as targeting miR-122 during chronic hepatitis C infection. Aside from therapeutics, the d

• El reto que est por venir

  2019-05-06

  

  El reto que está por venir en América Latina es que sus estados reconocidos como pluriétnicos no reciclen políticas indigenistas con el objeto de enmascarar su oposición Biotin Hydrazide manufacturer la diversidad cultural, ni tampoco revivan proyectos jerárquicos para atender las diversidades cultu

• br Eva Leticia Ordu a Trujillo investigadora del en uno

  2019-05-05

  

  Eva Leticia Orduña Trujillo, investigadora del en uno de sus más recientes libros , aborda un tema fundamental para explorar, debatir y profundizar sobre nuestras aún muy débiles democracias latinoamericanas, purchase thapsigargin través de la actuación de nuestros estados en sedes judiciales inte

• In a study of the

  2019-05-05

  

  In a study of the atrial pacing preference (APP) algorithm, Ogawa et al. [12] randomly programmed pacemakers as APP OFF and APP ON at 3 different settings (8, 16, and 33 cycles). The authors found that the most effective setting differed according to the patient and thus concluded that this therapy

• Introduction Several types of cancers including those origin

  2019-05-05

  

  Introduction Several types of cancers, including those originating in the breast, prostate, and lung, have a propensity to metastasize to the bones [1,2]. Bone metastases severely impair skeletal metabolism, and result in important clinical sequelae, such as excruciating chronic bone pain and the s

• br Results Twenty seven bone lesions

  2019-05-05

  

  Results Twenty-seven bone lesions were analyzed in 27 patients. Twelve of the patients were female and 15 were male. The mean age of the patients was 58 years with a range of 21–84 years. Ten lesions were determined to be malignant and 17 benign. Benign lesions of bone dropped in signal on out-of

• Prior case reports have described hematological remission in

  2019-05-05

  

  Prior case reports have described hematological remission in patients with myelofibrosis during treatment with bisphosphonates, but a phase II study investigating the effects of zoledronic 69 8 on patients with myelofibrosis showed responses in only 1 of 16 patients[13]. In conclusion, we report c

• An interesting finding in the study

  2019-05-05

  

  An interesting finding in the study of Ngabo and colleagues was that, after a huge drop in the number of admittances to hospital for rotavirus in 2013, there was no further fall the next year. As the researchers discuss, this finding might herald the beginning of a biennial pattern of rotavirus acti

• Primarily the management of GCTs has been curettage followed

  2019-05-04

  

  Primarily, the management of GCTs has been curettage followed by filling with bone cement [7,19]. However this has been associated with high recurrence rates. Additional treatment with adjuvants is often employed to reduce this recurrence. These adjuvants may include zinc chloride, bisphosphonates,

• No conviene ignorar la enorme influencia cultural de

  2019-05-04

  

  No conviene ignorar la enorme influencia cultural de Estados Unidos en la formación intelectual de Vasconcelos, so pena de caer en contradicciones. Ulises criollo se asienta en una tradición muy estadounidense, la de una fascinación por las cuestiones de la individualidad, la identidad y la autobiog

• Finalmente la parcela y heredad patrimonial del vecindario d

  2019-05-04

  

  Finalmente, la parcela y heredad patrimonial del vecindario de Xolloco Acatla –objeto de estas acérrimas desavenencias desde 1613– recibió protección legal. El espacio en el que se ubicaba la antigua cruz se institucionalizó y se construyó la ermita de Santa Cruz Acatla, antecedente inmediato de la

• El n mero de ofrece en una primera secci n

  2019-05-04

  

  El número 62 de ofrece, en una primera sección, tres artículos que se ubican en los campos de la literatura, las revistas culturales y en general las redes intelectuales en América Latina. Lucía Di Salvo León y Patricio Herrera González, en “¿Una poética del exilio? La revista y el exilio republican

• Venous gangrene treatment is based on therapeutic

  2019-04-30

  

  Venous gangrene treatment is based on therapeutic anticoagulation and thrombolytic therapy. Low-molecular weight heparin is a good choice for patients with active cancer and for pregnant women with good renal function, whereas heparin is used as an alternative in patients with poor renal function. M

• br Conclusions The experimental results

  2019-04-30

  

  Conclusions The experimental results in isolated sheep hearts presented herein clearly demonstrate that self-sustained rotors exist in the atria. Such rotors are the high frequency sources that give rise to the complex patterns of activation that characterize AF. More specifically, our results su

• br In Sanguinetti et al and Barhanin et al

  2019-04-30

  

  In 1996, Sanguinetti et al. and Barhanin et al. independently found that, when coassembled with the accessory subunit KCNE1, the KCNQ1 and KCNE1 complex could form a channel that very closely exhibited conductive and kinetic properties similar to that of cardiac IKs[14,56]. Kass and coworkers subs

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