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br Conclusive remarks Although the utilization of a single m
2018-11-08
Conclusive remarks Although the utilization of a single marker for the identification of stem ccr2 inhibitor may be risky, the stem cell antigen c-kit recognizes a population of CSCs that are self-renewing, clonogenic and multipotent in vitro and replace necrotic myocardium with functioning tissu
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prostaglandin f2 alpha br Materials and methods br Acknowled
2018-11-08
Materials and methods Acknowledgements We would like to thank Dr. Keisuke Okita and Prof. Shinya Yamanaka for providing the plasmids. Furthermore, we would like to thank Prof. Duncan R. Smith for proof reading the article. This work was supported by the Thailand Research Fund (MRG5980187), Nat
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Taurine is a free sulfur amino acid that is not
2018-11-08
Taurine is a free sulfur amino Recent data that is not incorporated in proteins. It is synthesized from methionine and cysteine by the rate-limiting enzyme cysteinesulfinic acid decarboxylase (CSD) that is found in the liver, the kidney and the brain, where it is localized in glial cells (Ripps & S
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The gene expression changes that occurred during the differe
2018-11-08
The gene expression changes that occurred during the differentiation process were consistent with our expectations of changes that must occur during neurogenesis. For example, there was a positive enrichment for genes involved in synaptogenesis and a negative enrichment for genes involved in progres
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We evaluated the functional properties of BM stromal cells i
2018-11-08
We evaluated the functional properties of BM stromal protease inhibitor cocktail isolated from a large number of ON and SCD-ON patients (n=340). Our CFE values for ON patients were consistent with those in the literature (Bernardo et al., 2007; Oreffo et al., 1998), although they were lower than CF
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dihydroergotamine Serelaxin RLN a recombinantly produced pep
2018-11-08
Serelaxin (RLN; a recombinantly-produced peptide based on the human gene-2 (H2) relaxin sequence; which represents the major stored and circulating form of human relaxin) exerts potent anti-fibrotic actions in the airways/lung (Bennett, 2009; Huang et al., 2011; Kenyon, Ward, and Last, 2003; Royce e
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br The adult subventricular zone a source of
2018-11-08
The adult subventricular zone: a source of neural stem cells The SVZ is the main reservoir of neural stem cells (NSCs) in the adult mammalian ppar agonist (Doetsch et al., 1997; Quinones-Hinojosa et al., 2006; Sanai et al., 2004). It is widely accepted that NSCs correspond to a pool of astroglial
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GSK503 Y a selective Rho associated kinase
2018-11-08
Y-27632, a selective Rho-associated kinase (ROCK) inhibitor, is known to facilitate hESC/hiPSC culture growth by diminishing dissociation-induced apoptosis (Ohgushi et al., 2010; Watanabe et al., 2007). We therefore compared doxycycline- and Y-27632-mediated hESC survival by the colony-forming assay
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The concept of neoblast specialization at wounds is
2018-11-08
The concept of neoblast specialization at wounds is important in understanding planarian regeneration and opens many avenues for future inquiry. For example, how is the neoblast response tailored to the identity of missing tissues? Do specialized neoblasts amplify their population, or do specialized
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br Author Contributions br Acknowledgments br Introduction N
2018-11-08
Author Contributions Acknowledgments Introduction Neurons in the CNS are particularly sensitive to injury and degenerative conditions that frequently result in cell death. Although adult neurogenesis persists in restricted vasopressin receptor antagonists areas (Gage, 2000; Hsieh, 2012; Kri
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br Conclusion The use of
2018-11-08
Conclusion The use of SR1 at 20% O2 proved to be the best condition for the expansion of HPSCs into larger cell numbers; however, the use of SR1 at 1% O2 resulted in an increase in the proportion of primitive HSCs in the sample. It will in the future be necessary to confirm the effectiveness and
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These studies add to a growing body
2018-11-08
These studies add to a growing body of information related to the role of p38 MAPK signaling in skeletal muscle progenitor cells. Over a decade ago, a requirement for p38 in the regulation of rodent myoblast differentiation was defined (Cuenda and Cohen, 1999; Zetser et al., 1999). Based on these pr
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br Results br Discussion WNT proteins in vivo are often
2018-11-08
Results Discussion WNT proteins in vivo are often secreted locally and presented to responsive Sulfo-NHS-LC-Biotin in a spatially controlled manner (Alexandre et al., 2014; Clevers et al., 2014; Farin et al., 2016; Goldstein et al., 2006; van den Heuvel et al., 1989). In this study, we presen
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There was some overlap in the final
2018-11-07
There was some overlap in the final variables left within the two models; pollution was important for both mental health measures, alongside alcohol use, how often the individual felt left out, and the self-reported happiness measure. Although happiness as a concept is not measured in the WEMWBS, on
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Isothermal bulk modulus at ambient
2018-11-07
Isothermal bulk modulus at ambient P-T condition (KT0; GPa) is one of the most important elastic properties for understanding the density and sound velocity features of Earth materials at the P-T conditions of the Earth\'s interior. Although the KT0 value of the Mg2SiO4-Rw has been reasonably well d
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