• Parkinson s disease PD is a neurological disorder

  2018-11-08

  

  Parkinson\'s disease (PD) is a neurological disorder characterized by the degeneration of dopaminergic neurons in the midbrain substantia nigra, leading to a reduction of dopamine in the striatum (Gaillard and Jaber, 2011). Currently, dopaminergic neurons can be obtained through differentiation from

• Herein we show that NEHUCB CD cell therapy accelerates wound

  2018-11-08

  

  Herein, we show that NEHUCB-CD34+ cell therapy accelerates wound closure in NOD/SCID mice, consistent with previous findings (Barcelos et al., 2009; Kim et al., 2010; Sivan-Loukianova et al., 2003). We used immunocompromised NOD/SCID mice for this study, as this mouse model is often used for human c

• Germ and somatic cells or pluripotent

  2018-11-08

  

  Germ and somatic cells, or pluripotent and differentiated Lomustine can be distinguished on the basis of their epigenetic states (Boland et al., 2009; Okita et al., 2007; Takahashi and Yamanaka, 2006; Yamanaka, 2012). We previously demonstrated that epigenetic reprogramming following somatic cell nu

• br Conclusive remarks Although the utilization of a single m

  2018-11-08

  

  Conclusive remarks Although the utilization of a single marker for the identification of stem ccr2 inhibitor may be risky, the stem cell antigen c-kit recognizes a population of CSCs that are self-renewing, clonogenic and multipotent in vitro and replace necrotic myocardium with functioning tissu

• prostaglandin f2 alpha br Materials and methods br Acknowled

  2018-11-08

  

  Materials and methods Acknowledgements We would like to thank Dr. Keisuke Okita and Prof. Shinya Yamanaka for providing the plasmids. Furthermore, we would like to thank Prof. Duncan R. Smith for proof reading the article. This work was supported by the Thailand Research Fund (MRG5980187), Nat

• Taurine is a free sulfur amino acid that is not

  2018-11-08

  

  Taurine is a free sulfur amino Recent data that is not incorporated in proteins. It is synthesized from methionine and cysteine by the rate-limiting enzyme cysteinesulfinic acid decarboxylase (CSD) that is found in the liver, the kidney and the brain, where it is localized in glial cells (Ripps & S

• The gene expression changes that occurred during the differe

  2018-11-08

  

  The gene expression changes that occurred during the differentiation process were consistent with our expectations of changes that must occur during neurogenesis. For example, there was a positive enrichment for genes involved in synaptogenesis and a negative enrichment for genes involved in progres

• We evaluated the functional properties of BM stromal cells i

  2018-11-08

  

  We evaluated the functional properties of BM stromal protease inhibitor cocktail isolated from a large number of ON and SCD-ON patients (n=340). Our CFE values for ON patients were consistent with those in the literature (Bernardo et al., 2007; Oreffo et al., 1998), although they were lower than CF

• dihydroergotamine Serelaxin RLN a recombinantly produced pep

  2018-11-08

  

  Serelaxin (RLN; a recombinantly-produced peptide based on the human gene-2 (H2) relaxin sequence; which represents the major stored and circulating form of human relaxin) exerts potent anti-fibrotic actions in the airways/lung (Bennett, 2009; Huang et al., 2011; Kenyon, Ward, and Last, 2003; Royce e

• br The adult subventricular zone a source of

  2018-11-08

  

  The adult subventricular zone: a source of neural stem cells The SVZ is the main reservoir of neural stem cells (NSCs) in the adult mammalian ppar agonist (Doetsch et al., 1997; Quinones-Hinojosa et al., 2006; Sanai et al., 2004). It is widely accepted that NSCs correspond to a pool of astroglial

• GSK503 Y a selective Rho associated kinase

  2018-11-08

  

  Y-27632, a selective Rho-associated kinase (ROCK) inhibitor, is known to facilitate hESC/hiPSC culture growth by diminishing dissociation-induced apoptosis (Ohgushi et al., 2010; Watanabe et al., 2007). We therefore compared doxycycline- and Y-27632-mediated hESC survival by the colony-forming assay

• The concept of neoblast specialization at wounds is

  2018-11-08

  

  The concept of neoblast specialization at wounds is important in understanding planarian regeneration and opens many avenues for future inquiry. For example, how is the neoblast response tailored to the identity of missing tissues? Do specialized neoblasts amplify their population, or do specialized

• br Author Contributions br Acknowledgments br Introduction N

  2018-11-08

  

  Author Contributions Acknowledgments Introduction Neurons in the CNS are particularly sensitive to injury and degenerative conditions that frequently result in cell death. Although adult neurogenesis persists in restricted vasopressin receptor antagonists areas (Gage, 2000; Hsieh, 2012; Kri

• br Conclusion The use of

  2018-11-08

  

  Conclusion The use of SR1 at 20% O2 proved to be the best condition for the expansion of HPSCs into larger cell numbers; however, the use of SR1 at 1% O2 resulted in an increase in the proportion of primitive HSCs in the sample. It will in the future be necessary to confirm the effectiveness and

• These studies add to a growing body

  2018-11-08

  

  These studies add to a growing body of information related to the role of p38 MAPK signaling in skeletal muscle progenitor cells. Over a decade ago, a requirement for p38 in the regulation of rodent myoblast differentiation was defined (Cuenda and Cohen, 1999; Zetser et al., 1999). Based on these pr

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