6XHis In addition to configurations for constitutive gene ex

2018-10-20

In addition to configurations for constitutive gene expression, we also tested the behavior of the Tet-on system (http://www.clontech.com) in which sequences encoding either GFP or mCherry expression were placed under the control of a doxycycline-responsive promoter. Although robust doxycycline-indu

br Experimental Procedures br Author

2018-10-20

Experimental Procedures Author Contributions Introduction Frontotemporal dementia (FTD) refers to a group of neurodegenerative diseases caused by focal but progressive neuronal loss, astrogliosis, and spongiosis in the frontal and temporal cortices associated with abnormal intracellular acc

Mitochondria are highly dynamic organelles with complex stru

2018-10-20

Mitochondria are highly dynamic organelles with complex structures involved in multiple processes, including energy metabolism, reactive oxygen species (ROS) generation, mitochondrial dynamics and distribution, and the induction of apoptosis. A number of recent studies have highlighted the key role

br Experimental Procedures br Author

2018-10-20

Experimental Procedures Author Contributions Acknowledgments This work was supported by grants to W.H. from the National Natural Science Foundation of China (81372258, 81572827), the Major State Basic Research Development Program of China (2013CB910802), and the Program for Professor of Spe

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2018-07-29