• br Conclusion Our findings bolster a prior study that

  2018-11-05

  

  Conclusion Our findings bolster a prior study that reports a positive association between political fragmentation and health disparities (Hutson et al., 2012). We show that Hutson and colleagues’ results have external validity to the 1970s and 1980s, a period in which important, and rapid, change

• The present study directly compares

  2018-11-05

  

  The present study directly compares attitudes about female genital cutting among Sudanese living in Switzerland to attitudes among Sudanese living in Sudan. Whether or not Sudanese immigrants are a special subset of the Sudanese population, and regardless of whether or not they move toward the value

• To examine whether the associations were consistent with a

  2018-11-05

  

  To examine whether the associations were consistent with a particular causal direction, we next explored associations between health and dgat1 inhibitor capacity in the opposite direction (Table 5). Here we found no evidence of an association between health and any community capacity measure aside

• br Methods br Results br Discussion Sequencing of the

  2018-11-05

  

  Methods Results Discussion Sequencing of the first human genome took more than a decade, completing in 2001, and costing more than US$2.7 million (Lander et al., 2001; Venter et al., 2001; NHGRI, 2010). In the subsequent decade, newer high-throughput genomic technologies, known as the Next-

• br Children who experience early

  2018-11-05

  

  Children who experience early life seizures, prolonged febrile convulsions being the most common scenario, often have demonstrable problems with learning and memory later in life (). Although some of the children may go on to have epilepsy (recurrent unprovoked seizures) later in life, the problem

• Barry and colleagues have successfully used sophisticated

  2018-11-05

  

  Barry and colleagues have successfully used sophisticated and demanding in vivo recording techniques to correlate behavior and azidothymidine function at the mesoscale level. This is but one example of the power of those techniques that attempt the difficult task of bridging the behavior of single

• Here we investigated the early

  2018-11-05

  

  Here we investigated the early effect of LEDGINs and evaluated their effect on HIV apigenin site distribution. In addition, we monitored the effect of LEDGINs on the establishment of the latent reservoir and investigated whether retargeting of integration could lead to a silent HIV reservoir resist

• Here we investigated the early

  2018-11-05

  

  Here we investigated the early effect of LEDGINs and evaluated their effect on HIV mtor inhibitor site distribution. In addition, we monitored the effect of LEDGINs on the establishment of the latent reservoir and investigated whether retargeting of integration could lead to a silent HIV reservoir

• br Materials and Methods br Results br

  2018-11-05

  

  Materials and Methods Results Discussion Although aberrant glycosylation is common in cancer and has been linked to PCa progression (Munkley et al., 2016), our understanding of what drives these cancer associated glycan changes has been scant and has relied upon anecdotal observations. Here

• As a potential therapeutic target

  2018-11-05

  

  As a potential therapeutic target, the pleiotropic actions of prolactin engender both excitement and frustration. Excitement, because clear beneficial actions shown in the lab seem to have huge potential for developing new treatments. Frustration, because with so many other tissues possibly influenc

• It must be taken into

  2018-11-05

  

  It must be taken into account that the compounds may also interact with the flexible N-terminal domain because NPRs have been derived by molecular simulation from human PrP (124–230 a.a.). To address this point, an in vitro-binding experiment (i.e. SPR) with purified PrPs (121–231 and 90–231 a.a.) w

• The significant SNPs lie in

  2018-11-05

  

  The significant SNPs lie in non-coding regions, as is common in GWAS where ~64% of identified SNPs lie in enhancer regions (Hnisz et al., 2013). Gene enhancer elements are noncoding segments of DNA involved in regulating transcriptional programs (Corradin and Scacheri, 2014). Their location is predi

• br Funding Sources br Role of Funding Source br

  2018-11-05

  

  Funding Sources Role of Funding Source Conflicts of Interests Author contributions Introduction The effect of disease modifying antirheumatic drugs (DMARDs) in rheumatoid arthritis (RA) on disease activity is generally presented using population means (Combe et al., 2015; Gabay et al.

• Furthermore such classification criteria that select

  2018-11-05

  

  Furthermore, such classification criteria that select a highly specific sub-population of SS participants (those with 2 out of 3 objective signs - focus score≥1, positive serology, and ocular staining score≥3) (Shiboski et al., 2012) could challenge external validity. Therefore, clinical trial resul

• The ongoing efforts to identify targeted therapy for

  2018-11-05

  

  The ongoing efforts to identify targeted therapy for dedifferentiated, metastatic PTC has led to empirically driven clinical trials of different tyrosine kinase receptor inhibitors that disrupt MEK, VEGFR, FGFR and other signaling pathways. These therapies were intended to slow disease progression,

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