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Given the recognized effects of bisphosphonates in
2019-06-12
Given the recognized effects of bisphosphonates in metastatic breast cancer [14,15] and that potential anticancer effects have been demonstrated in preclinical [16], translational [17], patients with cancer therapy-induced bone loss [18] and 1-Deoxynojirimycin based-studies [19,20] a number of clin
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There is strong agreement that
2019-06-12
There is strong agreement that HIV prevention should focus on approaches that are evidence based, but there is disagreement about how to obtain such rigorous evidence and whether this should refer only to randomised study designs. Pickles and colleagues\' report provides a concrete example of an eff
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Performance based financing often highlighted in Rwanda s st
2019-06-12
Performance-based financing, often highlighted in Rwanda\'s story, has had mixed results when applied elsewhere, partly because of breakdowns in execution. For example, the failure of the performance-based financing initiative in neighbouring Uganda was caused by challenges in setting targets, deliv
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br Imagine providing care for low birthweight LBW lighter th
2019-06-12
Imagine providing care for 900 000 low birthweight (LBW; lighter than 2500 g) newborn babies each year in sub-Saharan Africa—all attributable to preventable and treatable malaria. Many of these LBW babies will be born in rural and impoverished settings where access to health care is poorest and th
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Seg n el coeficiente de Gini que
2019-06-12
Según el coeficiente de Gini que mide la desigualdad, en la región es de 0.51, nivel de desigualdad sustancialmente más alto que otras zonas del mundo, al tener en cuenta que Estados Unidos tiene 0.378 y los países de la ocde 0.313. De ahí que el promedio simple de los valores en América Latina indi
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Obesity with excessive fat was an important risk
2019-06-11
Obesity with excessive fat was an important risk factor for the occurrence or progression of cardiac arrhythmia. As compared to abdominal fat, the amount of epicardial fat more correlates with the occurrences of atrial fibrillation, which suggests the distinctive arrhythmogenic effects of epicardial
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Igualmente podr a ampliarse su cr tica a la
2019-06-11
Igualmente, podría ampliarse su crítica O4I1 la modernidad occidental, entendida como proyecto civilizatorio orientado por la totalización de la racionalidad instrumental y el mito del progreso. La modernidad occidental no es sólo expresión de una racionalidad fetichizada. En tanto capitalismo globa
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br ECM cancer and metastasis
2019-06-11
ECM, cancer and metastasis For serine protease inhibitors to become cancerous they must acquire the ability to survive, grow and invade leading to malignant transformation, tumour formation and ultimately overt secondary metastasis. Abnormal ECM can promote these abilities and is a well-documente
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Introduction Atrial fibrillation AF is the most common cardi
2019-06-11
Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it commonly occurs after cardiac surgery. AF is often associated with stroke, congestive heart failure, and myocardial infarction, all of which contribute to the increase in the length of hospital stay, higher medical
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In Richard Walker and colleagues report the results
2019-06-11
In , Richard Walker and colleagues report the results of a case-control study of risk factors for stroke in Tanzania. Their study makes several important contributions. First, they provide the first information about importance of risk factors for stroke in urban and rural Tanzania, and confirm the
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br The introduction of direct acting
2019-06-11
The introduction of direct-acting antiviral drugs (DAAs) is changing the treatment options for hepatitis C calculating dilutions (HCV). These new medicines were initially marketed at a very high price, but several countries have negotiated favourable price reductions, and, in view of the low cost
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Asimismo el texto convoca a
2019-06-11
Asimismo, el texto convoca matrix metalloproteinases cuestionar muchos de los mitos sobre la guerra civil en Guatemala. No fue durante los años setenta que los revolucionarios guatemaltecos volcaron su mirada sobre el componente indígena como parte de las fuerzas insurgentes, tampoco fue en los oche
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br Introducci n El objetivo de este art culo es
2019-06-11
Introducción El objetivo de este artículo es lograr una aproximación al estudio de las disidencias sexuales de Argentina considerando el problema de abordarlas desde un paradigma importado de Estados Unidos. Para llevar esta tarea adelante, tomaremos algunos aportes de los ensayistas Néstor Perlo
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br The world population faces various types of climate
2019-06-11
The world population faces various types of climate-related hazards, and both the frequency and intensity of hazards are projected to increase in the future because of climate change. Since climate change could increase human health risks, many previous studies first estimated future temperatures
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br D microCT data Bone volume BV TV ranged
2019-06-11
3D microCT data Bone volume (BV/TV) ranged from 10.8 to 13.5% consistent with the published literature [18]. Trabecular thickness (Tb.Th), trabecular paricalcitol manufacturer (Tb.Sp), trabecular number (Tb.N) and bone surface per tissue area (BS/TV) values were also consistent with the range pub
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