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Mass spectrometry Matrix assisted laser
2024-07-26
Mass spectrometry. Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) MS experiment was performed in linear and positive-ion mode on a DE-STR instrument equipped with a nitrogen laser (PE Biosystems, Foster City, CA). Each spectrum was calibrated in the default mode in which 0.1%
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It has been well established that shortly after systemic inf
2024-07-26
It has been well established that shortly after systemic inflammation, NADPH oxidase and iNOS activity were increased in the myosin and lead to overproduction of reactive oxygen species (ROS) and NO [66]. Moreover, previous studies indicated that Ang II induced an increased level of NADPH oxidase an
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The beneficial treatment with several statins have been
2024-07-26
The beneficial treatment with several statins have been evaluated in AD patients (Kivipelto et al., 2005), with controversial results. It has been suggested that statins slow cognitive decline in mild to moderate AD (Miida et al., 2005). Treatment with atorvastatin, combined with other medications,
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The macrophage is the major cell type responsible for
2024-07-26
The macrophage is the major cell type responsible for cholesterol uptake and metabolism associated with the initiation and progression of atherosclerosis in focal areas of the arterial subendothelial space. In advanced atherosclerotic lesions of cardiovascular disease, cholesterol-induced macrophage
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In our study the expression levels
2024-07-26
In our study, the expression levels of adiponectin and its receptors in the uteri, conceptuses, and throphoblasts were determined by the stage of early pregnancy. Therefore, it could be hypothesized that the adiponectin system is regulated by the local hormonal milieu. Hormonal regulation in the ute
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e1 activating enzyme The H N mutation in
2024-07-25
The H373N mutation in exon 6 has not previously been reported [3], [4], [5], [6]; thus, this mutation appears to be a novel mutation. The functional expression study demonstrated that the H373N mutation results in almost complete loss of enzymatic activity. Thus, it is highly likely that the H373N m
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br Introduction Cadmium is a major component of
2024-07-25
Introduction Cadmium is a major component of heavy metal pollution. Phytoremediation is considered to be the more effective method for recovering contaminated soil [[1], [2], [3], [4]] via cadmium absorption, transport, and accumulation. Several cadmium-associated proteins have previously been we
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br Conclusion GroEL from RA CH was
2024-07-25
Conclusion GroEL from RA-CH-1 was expressed and purified. The recombinant RaGroEL protein exhibited ATPase activity, which cooperated with GroES in ATP hydrolysis. Furthermore, the expression pattern of groEL revealed that groEL was up-regulated during stress response. Further studies are warrant
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Additionally we used the predicted Cyp
2024-07-25
Additionally, we used the predicted Cyp19a1b amino CAY10603 australia sequence from a number of bony fish species to infer their genetic relatedness and found that R. quelen occupies an ancient position within the Siluriformes group. A phylogenetic tree was constructed and it included both full-leng
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Different antioxidants were described as useful biomarkers i
2024-07-25
Different antioxidants were described as useful biomarkers in monitoring response to treatment in human and veterinary medicine [33,65,66]. In the same line, Thiol and TAC also proved to be useful biomarkers in monitoring the post-ovariohysterectomy period in queens with pyometra, since antioxidants
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Bamboo shoots with their high nutritive http
2024-07-25
Bamboo shoots, with their high nutritive and therapeutic value, are now used for food fortification (Nirmala & Bisht, 2017). Several value-added products such as nuggets, crackers, chutney, snacks, cookies, cakes, chappaties, and buns have been prepared from bamboo shoots (Table 3). Dietary fiber fr
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Breast Cancer Although androgens have been considered to be
2024-07-25
Breast Cancer: Although androgens have been considered to be a risk factor in prostate cancer they have been recommended to treat breast cancers. Even before the discovery of SERMs and aromatase inhibitors, steroidal androgens such as medroxyprogesterone and fluoxymesterone were used to treat breast
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Perhaps the first evidence of AMPKs therapeutic ability
2024-07-25
Perhaps the first evidence of AMPKs therapeutic ability in DM1 came from Thomas Cooper’s laboratory where they demonstrated that insulin-independent glucose uptake was unaffected in human DM1 muscle Alda 1 treated with MET, an AMPK activator and first-line therapy for type 2 diabetes mellitus [76].
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br Acknowledgements This work was supported by
2024-07-25
Acknowledgements This work was supported by Programme Grants from the MRC and the Wellcome Trust (SGC-C and MF). CB was in receipt of a Marie Curie Intra-European Fellowship during part of this work. We thank past and present members of our group for numerous valuable discussions throughout these
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There are two ways to transport FFAs into cells First
2024-07-24
There are two ways to transport FFAs into cells. First by passive diffusion. Second as the putative long-chain fatty Irinotecan transporters are proposed, CD36 the plasma membrane-associated fatty acid-binding protein (FABPpm) and fatty acid transport proteins (FATP) [11], where CD36 is responsible
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